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ImmunityBio, Inc. is a clinical stage immunotherapy company. It develops next generation therapies that drive immunogenic mechanisms for defeating cancers and infectious diseases. The company's immunotherapy platform activates both the innate and adaptive immune systems to create long term immunological memory. ImmunityBio was founded by Patrick Soon-Shiong in 2014 and is headquartered in San Diego, CA.

ImmunityBio Inc

ImmunityBio is trending as retail investors speculate on potential Russell 1000 index inclusion, driving significant options activity and a high-volume surge that has intensified the ongoing conflict between bullish market participants and short sellers. Investors are closely watching for follow-through momentum and potential catalysts, including upcoming Q2 earnings and international clinical milestones, as they look to capitalize on the recent price action.

SELLAS Life Sciences Group, Inc. is a clinical stage biopharmaceutical company, which engages in the development and commercialization of immunotherapeutic for cancer indications. Its product pipeline includes galinpepimut-S. The company was founded by Angelos M. Stergiou on April 3, 2006 and is headquartered in New York, NY.

SELLAS Life Sciences Group Inc

SELLAS Life Sciences is trending as a high-stakes binary battlefield, with investors closely monitoring the Phase 3 REGAL trial data and imminent survival event disclosures while short sellers face intensifying pressure from significant interest and elevated borrow rates. Community discourse centers on a potential short squeeze and buyout speculation, as retail traders debate the clinical implications of the trial's duration and its broader potential as a cancer treatment platform.

Bitcoin is the world's first decentralized cryptocurrency, created in 2009 by the pseudonymous Satoshi Nakamoto. It enables peer-to-peer electronic cash transactions without intermediaries like banks or governments, operating on a blockchain secured by Proof of Work mining and the SHA-256 cryptographic algorithm.   With a fixed supply cap of 21 million coins and programmatic halvings every four years that reduce miner rewards, Bitcoin is designed as a deflationary digital asset often called "digital gold." Its value stems from solving the double-spending problem without trusted intermediaries, creating the first truly scarce digital asset with censorship resistance and permissionless access that no government, corporation, or individual can control.  Bitcoin operates as a decentralized peer-to-peer network where transactions are recorded on a public ledger called the blockchain, distributed across thousands of computers globally. Transactions are grouped into blocks added approximately every 10 minutes through mining, where specialized computers compete to solve complex mathematical puzzles.   Bitcoin has achieved mainstream adoption through multiple vectors. The January 2024 SEC approval of 11 spot Bitcoin ETFs opened Bitcoin investment to traditional finance participants, and corporations like Strategy (formerly MicroStrategy) are using Bitcoin as a treasury reserve asset to protect against currency debasement, offering MSTR holders amplified exposure to Bitcoin.   The Bitcoin ecosystem continues to evolve with innovations like Ordinals, which emerged in January 2023 to enable NFT-like functionality directly on Bitcoin, and BRC-20 tokens, an experimental standard for creating fungible tokens using Ordinal inscriptions. BTCFi (Bitcoin Finance) represents emerging financial applications extending beyond Bitcoin's traditional role, with protocols like Babylon allowing Bitcoin holders to stake BTC to secure Proof of Stake chains.

Bitcoin

Bitcoin is currently experiencing intense market debate as investors weigh the impact of institutional accumulation against concerns regarding potential liquidation risks tied to large corporate holdings. The community remains deeply divided, with bulls pointing to strong long-term holder resolve and potential regulatory catalysts, while bears focus on technical breakdowns and broader macroeconomic volatility.

Zevra Therapeutics, Inc. is a commercial-stage rare disease company that combines science, data and patient needs to create therapies for diseases with limited or no treatment options. The firm focuses on the treatment of rare neurological and sleep conditions such as certain Urea Cycle Disorders, Niemann Pick Disease Type C and Idiopathic Hypersomnia. The company receives royalties for AZSTARYS from its commercial partner Corium. The company was founded by Christal M. M. Mickle and Travis C. Mickle on October 30, 2006 and is headquartered in Celebration, FL.

Zevra Therapeutics Inc

Zevra Therapeutics is trending as investors react to a significant patent expansion that secures exclusivity for its flagship drug, MIPLYFFA, through 2041. The community is actively discussing this move as a major catalyst that bolsters the company's long-term valuation and serves as a primary point of interest for potential M&A suitors.

Upstart Holdings, Inc. engages in the provision of a cloud-based artificial intelligence lending platform. It operates through the following segments: Personal Lending, Auto Lending, and Other. The Personal Lending segment focuses on unsecured personal loans and small dollar loans. The Auto Lending segment is involved in auto refinance and auto retail loans. The Other segment refers to HELOCs and other. The company was founded by David Joseph Girouard, Anna Mongayt Counselman, and Paul Gu in December 2013 and is headquartered in San Mateo, CA.

Upstart Holdings Inc

Upstart Holdings is seeing renewed investor attention as the community focuses on its AI-driven credit underwriting as a potential infrastructure play, despite ongoing frustration with the stock's recent volatility and sensitivity to macro headwinds. Discussions are dominated by speculation over a potential short squeeze, upcoming product catalysts, and comparisons to other fintech peers in the sector.

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SPY is experiencing heightened volatility and intense social media chatter as market participants react to the rapidly evolving geopolitical tensions between the U.S. and Iran. The community remains deeply divided, with many actively debating whether the recurring cycles of escalation and sudden diplomatic de-escalation are genuine developments or strategic market manipulation designed to influence sentiment ahead of the holiday week.

Oscar Health, Inc. is a healthcare insurance company, which serves its customers through a technology platform. It offers individual and family, small group and medicare advantage plans, and technology platform to others within the provider and payor space. The company was founded by Mario Tobias Schlosser, Kevin Nazemi, and Joshua Kushner on October 25, 2012 and is headquartered in New York, NY.

Oscar Health Inc - Ordinary Shares - Class A

Oscar Health is experiencing strong momentum and bullish sentiment as it breaks through key multi-year resistance levels, driven by its recent profitability inflection and aggressive growth guidance. The community is actively discussing the stock's significant recovery from previous lows, with many traders focused on the stock's potential for further expansion toward higher price targets while debating the balance between technical momentum and fundamental scaling.

ON Semiconductor Corp. engages in the provision of intelligent power and sensing solutions with a primary focus on automotive and industrial markets. It operates through the following segments: Power Solutions Group (PSG), Analog and Mixed-Signal Group (AMG), and Intelligent Sensing Group (ISG). The PSG segment offers discrete, module, and integrated semiconductor products that perform multiple application functions, including power switching, signal conditioning, and circuit protection. The AMG segment designs and develops analog, mixed-signal, power management integrated circuits, sensor interface devices, power conversion, signal chain, and voltage regulation devices. The ISG focuses on the design and development of complementary metal oxide semiconductor image sensors, image signal processors, single photon detectors, including silicon photomultipliers, single photon avalanche diode arrays, and short-wavelength infrared products, as well as actuator drivers for autofocus and image stabilization. The company was founded on July 4, 1999 and is headquartered in Scottsdale, AZ.

ON Semiconductor Corp.

ON Semiconductor is facing heightened volatility as investors weigh the long-term strategic benefits of its all-stock acquisition of Synaptics against immediate dilution concerns. While some in the community view the significant price drop as an overreaction and a value-buying opportunity for a play on physical AI, others are focusing on the complex integration and potential for continued short-term pressure.

CRISPR Therapeutics AG is a gene editing company, which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Its CRISPR/Cas9 platform is a gene editing technology that allows for precise, directed changes to genomic DNA. The firm offers a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, and rare diseases. The company was founded by Rodger Novak, Emmanuelle Charpentier, Shaun Patrick Foy, Matthew Porteus, Daniel Anderson, Chad Cowan, and Craig Mellow on October 31, 2013 and is headquartered in Zug, Switzerland.

CRISPR Therapeutics AG

CRISPR Therapeutics is currently facing significant volatility driven by a major capital raise through convertible senior notes, which has fueled investor concerns over dilution despite the company's strong existing cash position. While the community is debating management's strategic intentions, active discussions remain focused on upcoming clinical trial data readouts and the broader long-term potential for gene editing as a disruptive healthcare theme.

Madrigal Pharmaceuticals, Inc. engages in the development and commercialization of therapeutics for metabolic dysfunction-associated steatohepatitis. The company was founded by Rebecca A. Taub, Frederick Bernard Craves, and Edward Chiang on March 10, 2000 and is headquartered in West Conshohocken, PA.

Madrigal Pharmaceuticals Inc

Madrigal Pharmaceuticals is trending due to anticipation surrounding its ongoing commercial rollout of Rezdiffra and significant investor interest in potential M&A scenarios involving major industry players. Community sentiment remains mixed, with bullish supporters highlighting the company's first-mover advantage and pipeline expansion, while others debate the impact of high R&D spending and the competitive threat from emerging MASH treatments.

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ETFs to Follow Amid U.S.-China Summit 

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Monday’s moves, triggered by a significant military escalation between the U.S. and Iran, added to the sharp selloff in Chinese tech stocks in recent months.


What Lies Ahead for China ETFs in the New Year of the Horse?

China ETFs enter the Year of the Horse with cheap valuations, AI momentum and policy support, but property woes, weak consumption and geopolitics may keep volatility elevated.

Alibaba Stock Climbs Premarket After 6-Day Losing Streak

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Hold rates steady

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Fed decision day is here - Kevin Warsh chairs his first FOMC meeting with markets pricing a hold at 3.50%-3.75% but watching for a hawkish shift. Vote on what you expect to be decided today, then drop your prediction for the first rate cut or hike in the comments.

What do you expect the Fed to decide at its FOMC meeting today? 
 
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